My 2008 Tahoe, 5.3 Flexfuel, AFM, 4 spd, will lose about a liter by the 5000km mark. I check it every week to be safe. Its important to keep in mind that if you run your vehicle down to 0 % on the oil life monitor, you could potentially run through 10000kms or more. Im not condoning the oil consumption issue, just reminding folks that if you have the AFM, its important to do regular checks at the dipstick. I also have a 2011 GMC Sierra 1500, 5.3, 6 spd, no AFM... got 100000kms on that as well and doesnt burn a drop.
Forgot to mention, I used 100% synthetic in the Tahoe, and also switched to semi-synth and dino and didnt see much of a difference in consumption between them.