I have a 2015 Suburban with the same issue. It is a rumble (like a rear window is down) and only happens between 40-50 for the most part, peaking at 45 mph. Towing is much worse, which makes me think it's the transmission. Also, the vibration surges. For example, if I put the vehicle in cruise control at 45 mph, the vibration increases and decreases rhythmically. While towing a single axle trailer with about 1,500 pounds of cargo, the Suburban would violently shake at times, and then be perfectly smooth other times. The dealership can't figure it out, but they are trying hard for me and I appreciate it.