Yes it works with the Bose. The system I purchased is this one . It is a sub w/ 200w app and and the wiring harness. The only wires you run are one power to the battery, and the other wire taps in to an existing speaker line (there is a ground line also that you'll secure to a frame bolt near parking brake). The wire tap was done in the factory harness on driver's side under parking break, (see my 2nd picture in the sequence above). There are 2 wires twisted together (brown with blue stripe and solid blue wire) tap into those. I emailed Kicker to verify, and they even sent me a pdf with good install instructions. PM me if you want a copy.