Having similar issues with very high DEF usage, Just bought the truck last month primarily to tow 25 ft travel trailer (4700 lbs dry, est 5700 lbs loaded). On our first trip with travel trailer from our home in The Villages to Pensacola, 400 miles. Not long after leaving the house got a message stating we had 2000 mile range on the DEF. Checked gauge and it showed 3/4 full. Just on the other side of Tallahassee, roughly 250 miles into the trip, message came on the we had 300 mile range, Gauge showed 1/4 full. 100 miles later, 50 miles from Pensacola, warning came on stating DEF tank was empty. Bought DEF once in Pensacola and filled it for trip back to The Villages. Same problem on the return trip, used up entire Def tank on 400 trip. Difference this time was when DEF ran dry max speed was immediately reduced to 65 mph. I estimate that I used about 8 gallons of DEF for the 4 day 1000 mile trip, 800 of that towing. DEF usage calculation was 1 gal of DEF for every 11 gal of Diesel. Significantly higher than what I was told DEF usage would be. During the entire trip the check engine did not come on. The check engine light finally came on the following day when not towing the trailer. Took vehicle to dealer and they have diagnose a faulty particulate sensor. Problem is the part is backordered with no estimated time of delivery. Have been told not to do anymore towing until part has arrived. Reading through other threads, it appears this engine might had not been tested fully under towing conditions. Emission systems appears to be overcompensating when fuel usage increases when towing, I have experience minimal DEF usage when driving truck not towing,