No one has followed up for awhile....I have a '22 2500HD (Crew cab) 4X4, AT4 trim. It does NOT have any blocks in back to remove. (1) Drop shackles. If you drop the rear too much you will lose the suspension travel for towing your trailer. For some real numbers, for my truck, the travel is 4.5" until bump stop, empty. If I use drop shackles to drop 2", there is only 2.5" left until axle hits the bump stop. My GN horse trailer drops rear 1", so that would leave only 1.5" of suspension travel - definitely not enough for any real towing. I would think your 5th wheel drops the rear more than mine. (2) So just cut the bump stops, right? That should regain the suspension travel, right? Well my shocks bottom out just 1" further, so if I cut the bump stops 1", it risks bottoming out on the shocks (ouch). So have to change the shocks too. This why I went with only 1" drop shackles. (3) With only 1" drop in in the back, I don't have to adjust the front. But it appears from other posts/videos that the stock torsion bars will adjust only an inch or two. And if you do lower the front, you have to at least get an alignment, not to say of checking first about the front bump stops and shocks bottoming out. As "mtbadbob" indicates, not much you can do with these newer, much taller HD trucks.