'07 Escalade ESV, 160k miles, all stock, 265/65/18 Towing 24' Express cruiser, about 7500lbs
Photo - Purchased truck 3-days before 2500 mile road trip to pick-up (just purchased) boat. Found that the rear shock air boots were blown ... no leveling (plus a few hundred pounds in the back).
Highway only : Below 70mph = 10.5 to 11 mpg
Above 70mph = 9.5 to 10 mpg
Tucking in behind 40+ foot trailers = gain of about .5 mpg
Our last two 3/4 ton Sunburbans, both 2001s (had 28' Express Cruisers at that time, 10k+ lbs), one with 6.0 and other with 8.1, both got just below 12-mpg on highway UNLOADED. Got 10-mpg average daily use .... if not hot-rodding around. Never calculated towing MPG.