Had this issue occur on my 2020 last night. Occurred in the middle of a long drive and we noticed the whole infotainment was unresponsive. XM Radio played even after doors shut, locked, reopened. Shut locked, etc. Onstar was also non responsive. Finally called Onstar and she had to reset it remotely then we did a workaround of turning off the truck, opening the driver door. Closing and waiting inside the truck until the Onstar light went off then back on. That fixed it. Software is up to date. It’s going to the dealership today. Back in the 2000s I had a similar thing occur in a Cadillac CTS. After the third trip to dealer did not fix, I was going to claim lemon law. Instead, GM gave me a brand new lease in a new model at same cost. Seems they wanted to avoid the lemon process as much as possible. Sent from my iPhone using Tapatalk