I also have a 2015 5.3, my truck has a dod delete, cam, dyno tuned, all lifters solid. So it's always v8. I did the cam and dod delete at 100,000 miles, I'm at 130,000 miles now. This started with a p2096 code with the same symptoms . Replaced cats, o2 sensors, spark plugs, did vaccum smoke test, still have similar symptoms as guy above, low power, sputtering. Seemed like every time i replaced something she ran good again for a couple days and then back to ******. I did find an exhaust leak from when I installed the cat . Fixed that, cleared the check engine light and managed to drive it almost a week without a check engine light, it even auto cleared the permanent p2096 code.
Then today I got the engine light again with the same old P2096 as well as a new P0324. Knock sensor .
At this point I'm nervous that I have a bad cam lobe and damaged lifter.
Any thoughts?