I'm guessing the fuel mileage for the three motor combinations is fairly close together for highway driving because all three engines go to four cylinders as much as possible, thus they are close to equivalency when running on four cylinders in terms of amount of power produced to keep the truck at speed. As we all know, engines are big air pumps, the air to fuel mixture is optimally around, what, 15:1 (somebody help me here with the correct ratio), and the power produced by exploding that mix per cylinder explosion would thus seem to be a constant amount. Racing engines turn up the RPMs, thus developing more power strokes resulting in more power per second. The V-6 has fewer cylinders and would be expected to have lower parasitic drag than the V-8s and I'd love to hear someone tell us how much this extra valve train and cylinder/crank frictional drag affects highway mileage.
A whole lot of words to say that the engines when on V4 are generating the same amount of power and thus shoving the same amount of air and fuel mix into the engine. The differences are likely the two fewer cylinders parasitic losses and that, it seems, may not a big energy loss factor at highway speeds. When sitting in city traffic, the V-6 has a big advantage versus the V-8s as those V-8s have to keep feeding two extra cylinders with a air/fuel mix.
I'd like to know more about the fuel/air mix going richer when under an increasing load, like going up a hill, and leaning out when going down the hill. With today's air flow mass sensor, direct injection and computerization technology, you've got to figure there is a lot of that kind of action taking place in our 2014 version engines.
Merry Christmas to all!