Sagamfg

Today I was driving and out of no where I noticed a ruff idle / acceleration. Very ruff idle at a stop and the check engine light began flashing along with a lit traction control light. Also it was shifting very hard especially when decelerating. I took it to the parts store to get it scanned and got P0301 cylinder 1 misfire along with C0299-00 brake booster large vacuum leak. C0196-5A yaw rate signal- not plausible , U0401-71 invalid data received from engine control module - invalid data. What could be the culprit? Thanks in and Vance (2014 Silverado z71 4x4 5.3 122k)