We always roll windows down on ramp just in case escape route is needed. If alone, I also use parking brake. We mostly boat on inland lakes so no slimy, slick ramps like coastal ramps.
Slightly different situation but we had flat on truck rear tire with 5th camper hooked to it. We made overnight stop at a Walmart and woke to a flat tire (from puncture in tire where pin pressure caused slow leak down, not a Walmart vandal). Using truck jack and front lifting legs of 5er, I lifted rear tire up and changed it with 5er attached.