Disclaimer; I'm not a motorhead either. This is what I've learned after some homework. If anyone knows better, please enlighten me!
Under the intake manifold, there are 2 semi-rigid fuel pipes that need to be removed when servicing lifters on the 5.3
GM part #12677002 and #12679463. I did read somewhere that GM specifies 'single use' and these parts are not to be reused. I've looked at other dealer service invoices for lifter replacement and these pipes were replaced.
My Sierra build date is 12/20 and I've babied that truck like my first born child. 2 lifters collapsed simultaneously at freeway speed leaving the truck undriveable. I hope you escape this curse!!