I was thinking in terms of an objective measure of compression, like how close you are to the overload springs or how close you are to the stop bumpers. Our eyes are pretty good at estimating measurements in the 0 to 6 inch range, and especially good in the 0 to 3 inch range.
I have not had enough loading experience with my new truck to be there yet, but on my old K2500 truck I could certainly tell you within 500 lbs how much was in the bed by looking at how far the axle was from the bumpers based on knowing the weights from weighed dump runs.
I just think tire pressure won’t get you close because the pressure change isn’t that great. The TPMS only displays whole numbers, is slow, and has hysteresis built in. In addition, most of the weight change is handled by deformation of the tire and increase in the footprint rather than straight pressure rise as if the tire was like a piston in a cylinder. If you could measure the footprint and the pressure change you’d get closer, but even then the footprint pressure on the ground isn’t uniform.
I think we are close to seeing real time load displays in new truck, but they will be based on sensors associated with the suspension system and not the tires for good reason. In the meantime, I still think measuring or eyeballing suspension compression is going to be more accurate than trying to use TPMS. Nothing wrong with looking at it and seeing if you can make it work for you, though.