cylinder 2 misfire

[Adam Richards]

2017 chevorlet silverado 1500 4x4

recently been running rough and throwing codes for cylinder 2 misfire. replaced plug and ignition coil on that cylinder. good for about 2 months and then acting up again. also throwing code uo401 for multiple diff components. example: transfer case control module, anti lock brake system.  also code b127e .  not sure if i have a wiring issue that is causing the problem or a bad ecm. or maybe both. any help or experience in this situation would be appreciated.  

edit: code: uo401 invalid data received from ecm/pcm a ( anti lock brake system)

        code: uo401 invalid data recieved from ecm/pcm a ( transfer case control module)

        code: b127e human machine interface module

        code: po302 cylinder 2 misfire detected

Edited March 15, 2023 by Adam Richards
add additional info

[BO TIE 1]

You may be having some ground issues. Check out YouTube there are plenty of videos on ground locations. Hope you get it figured out. Good luck. 

[richard wysong]

Maybe a bad injector or compression problem for the misfire, Welcome to the forum! Please when you post codes post the definitions, there are more than 18000 possible codes and no one knows all of them. Also you will get better responses to your questions. What brand of coil did you use for replacement? There is a LOT of white box trash out there that has VERY short life spans

[Adam Richards]

31 minutes ago, richard wysong said:

Maybe a bad injector or compression problem for the misfire, Welcome to the forum! Please when you post codes post the definitions, there are more than 18000 possible codes and no one knows all of them. Also you will get better responses to your questions. What brand of coil did you use for replacement? There is a LOT of white box trash out there that has VERY short life spans

Not sure right off hand of the brand. but i did swap ignition coils and plugs/wires  on cylinders 2 and 4 and it still throws the same codes. ( cylinder 2 misfire) i also had a couple random misfires on other cylinders within the last week. with a count of 3 or less. 

[richard wysong]

So that eliminates that, You can try swapping the injectors around and taking a compression test. You might want to check power and signal to the coil and the injector first