Multiple code issues on my 14 GMC Sierra SLT 5.3

[Gutz66]

Hello, Hoping to find some help here as I am at my wits end. Threw a code P0030 originally and then a P0300. I assumed the O2 sensors were up for replacement due to very high mileage I have. I ended up replacing both the upstream and downstream sensors so that rules them out. Once I did that, truck ran good for about 5 min. Started to stumble and lack power and poor idle. Now I have P0300, P0500, P0030, P0031, P0135, P0137 and P0172. I had already replaced the fuel injectors, fuel rails and plugs about 3 years ago max. My INNOVA 3160e scanner is not pointing out a specific bank for misfire at this time, just generic codes. Any thoughts out there? Hate to take it to the dealership but I am starting to run out of options.  Thanks

Edited January 6, 2023 by Gutz66
misspelling and more detail needed